A holistic design perspective on media capturing and reliving

Copyright © 2016 ACM. People capture far more media than they are able to relive. In this paper we identify the discrepancy between media capturing and media reliving from a design perspective. We propose a holistic perspective, that invites designers of media experiences to considering all three interdependent aspects of the media process: media capturing interaction, specific media, and media reliving interaction. By adopting this view, we aim to ensure that the media that is captured will be both necessary and appropriate for the intended reliving experience. We illustrate our perspective with three design concepts. Finally, in the discussion we present several topics related to media capturing and reliving

Informing design for reflection: An overview of current everyday practices

© 2016 ACM. There is an increasing interest in HCI in designing to support reflection in users. In this paper, we specifically focus on everyday life reflection, covering and connecting a broad range of topics from someone's life rather than focusing on a very specific aspect. Although many systems aim to support reflection, few are based on an overview of how people currently integrate reflection in everyday life. In this paper, we aim to contribute to this gap through a questionnaire on everyday life reflection practices combining both qualitative and quantitative questions. Findings provide insights in the broad range of people that engage with reflection in different ways. We aim to inform design through four considerations: rumination, timing, initiative and social context

Do we ruin the moment? Exploring the design of novel capturing technologies

Copyright © 2015 ACM. By capturing our experiences we often strive to better remember them in the future. However, the act of media capturing also influences these same experiences in the present, an area which is underexplored. This paper describes a study with the aim to inform the design of novel media capturing strategies. Adopting an approach of defamiliarization based on intervention and reflection, we strive to gain insights in the influences of future capturing technologies on the experience of a day out. We conducted an exploratory study in which 28 students went on a day out and used a variety of capturing strategies. Individual and group reflections on the experience during this day identified several important aspects that media capturing influences: engagement, perception & attention and social activity. The paper concludes with implications for design and proposes three potential future directions for media capturing, that instead of disturbing the moment enhance the experience

The discrimination capabilities of Micromegas detectors at low energy

The latest generation of Micromegas detectors show a good energy resolution, spatial resolution and low threshold, which make them idoneous in low energy applications. Two micromegas detectors have been built for dark matter experiments: CAST, which uses a dipole magnet to convert axion into detectable x-ray photons, and MIMAC, which aims to reconstruct the tracks of low energy nuclear recoils in a mixture of CF4 and CHF3. These readouts have been respectively built with the microbulk and bulk techniques, which show different gain, electron transmission and energy resolutions. The detectors and the operation conditions will be described in detail as well as their discrimination capabilities for low energy photons will be discussed.Comment: To be published in the proceedings of the TIPP2011 conference (Physics Procedia

Absorption and Intestinal Metabolic Profile of Oleocanthal in Rats

Oleocanthal (OLC), a phenolic compound of extra virgin olive oil (EVOO), has emerged as a potential therapeutic agent against a variety of diseases due to its anti-inflammatory activity. The aim of the present study is to explore its in vivo intestinal absorption and metabolism. An in situ perfusion technique in rats was used, involving simultaneous sampling from the luminal perfusate and mesenteric blood. Samples were analysed by UHPLC-MS-MS for the presence of oleocanthal (OLC) and its metabolites. OLC was mostly metabolized by phase I metabolism, undergoing hydration, hydrogenation and hydroxylation. Phase II reactions (glucuronidation of hydrogenated OLC and hydrated metabolites) were observed in plasma samples. OLC was poorly absorbed in the intestine, as indicated by the low effective permeability coefficient (2.23 ± 3.16 × 10-5 cm/s) and apparent permeability coefficient (4.12 ± 2.33 × 10-6 cm/s) obtained relative to the values of the highly permeable reference compound levofloxacin (LEV). The extent of OLC absorption reflected by the area under the mesenteric blood-time curve normalized by the inlet concentration (AUC) was also lower than that of LEV (0.25 ± 0.04 vs. 0.64 ± 0.03, respectively). These results, together with the observed intestinal metabolism, suggest that OLC has a moderate-to-low oral absorption; but higher levels of OLC are expected to reach human plasma vs. rat plasma

Reply to 'Comment on López-Yerena et al. 'Absorption and intestinal metabolic profile of oleocanthal in rats' Pharmaceutics 2020, 12, 134'

Recently, in February 2020, we published a study exploring the intestinal absorption and metabolism of oleocanthal (OLC) in rats. A single-pass intestinal perfusion technique (SPIP) was used, involving simultaneous sampling from the luminal perfusate and mesenteric blood. Later, comments on our published paper were released, requesting clarification of specific data. In this detailed reply, we hope to have addressed and clarified all the concerns of A. Kaddoumi and K. El Sayed and that the scientific community will benefit from both the study and the comments it has generated

Cancer survivors who fully participate in the PROFILES registry have better health-related quality of life than those who drop out

Purpose Attrition and subsequent missing data pose a challenge in longitudinal research in oncology. This study examined factors associated with attrition in the PROFILES registry, and its impact on observed health-related quality of life (HRQOL) estimates. Methods Sociodemographic, clinical, and HRQOL data were collected annually from a cohort of 2625 colorectal cancer survivors between 2010 and 2015. Participant characteristics according to time of dropout were compared using analysis of variance and chi-square tests. Predictors of attrition were examined in logistic regression analysis. Multilevel linear mixed models were constructed to investigate associations between attrition and HRQOL over time. Results Participants who dropped out were more likely to be female (OR = 1.23, CI = 1.02–1.47), older (OR = 1.20, CI = 1.09–1.33), less educated (OR = 1.64, CI = 1.30–2.11), and to have depressive symptoms (OR = 1.84, CI = 1.39–2.44) than full responders, and less likely to have high socioeconomic status (OR = 0.74, CI = 0.61–0.94). Participants who dropped out earlier reported significantly worse HRQOL, functioning, and psychosocial symptoms, which declined at a steeper rate over time, than full responders. Conclusions Cancer survivors’ HRQOL may be overestimated in longitudinal research due to attrition of the most unwell participants. Implications for Cancer Survivors Cancer survivors with the poorest health are at risk of dropping out of PROFILES and possibly withdrawing from other activities. Optimizing participation in PROFILES—a potential mechanism for providing information and access to support—is an avenue for keeping this group engaged

MIMAC : A micro-tpc matrix for directional detection of dark matter

Directional detection of non-baryonic Dark Matter is a promising search strategy for discriminating WIMP events from background. However, this strategy requires both a precise measurement of the energy down to a few keV and 3D reconstruction of tracks down to a few mm. To achieve this goal, the MIMAC project has been developed. It is based on a gaseous micro-TPC matrix, filled with CF4 and CHF3. The first results on low energy nuclear recoils (H, F) obtained with a low mono-energetic neutron field are presented. The discovery potential of this search strategy is discussed and illustrated by a realistic case accessible to MIMAC.Comment: 6 pages, Proc. of the fifth international symposium on large TPCs for low energy rare event detection, Paris, France, Dec. 2010. To appear in Journal of Physic

X-ray detection with Micromegas with background levels below 10−6^{-6} keV−1^{-1}cm−2^{-2}s−1^{-1}

Micromegas detectors are an optimum technological choice for the detection of low energy x-rays. The low background techniques applied to these detectors yielded remarkable background reductions over the years, being the CAST experiment beneficiary of these developments. In this document we report on the latest upgrades towards further background reductions and better understanding of the detectors' response. The upgrades encompass the readout electronics, a new detector design and the implementation of a more efficient cosmic muon veto system. Background levels below 10$^{-6}$keV$^{-1}$cm$^{-2}$s$^{-1}$ have been obtained at sea level for the first time, demonstrating the feasibility of the expectations posed by IAXO, the next generation axion helioscope. Some results obtained with a set of measurements conducted in the x-ray beam of the CAST Detector Laboratory will be also presented and discussed